UPDATES :Canine Longevity Research 1. Loyal's STAY Study for LOY-002 Loyal, a biotech company focused on extending canine lifespan, has launched a significant clinical trial named the STAY study. This trial involves 1,000 dogs across 50 veterinary clinics and is designed to evaluate LOY-002, a drug candidate aimed at extending the healthy lifespan of large-breed dogs. The STAY study is one of the most ambitious longevity trials conducted in companion animals to date. 2. Dog Aging: rapamycin—a drug known for its anti-aging properties in laboratory models. Early research has shown that rapamycin may improve heart muscle function, cognitive performance, and mobility in dogs. These trials are part of a broader effort to understand the biology of aging and potentially extend the lifespan and healthspan of companion dogs.